Searchable abstracts of presentations at key conferences in endocrinology

ea0063ep99 | Pituitary and Neuroendocrinology | ECE2019

Challenges in management of diabetes insipidus with impaired thirst perception

Siddique Rana , Tauni Rahat

A 37-year-old female, referred by gynaecologist with low prolactin and free T4 after work up for secondary amenorrhea despite removal of contraceptive coil 18 months ago. Her only daughter was born seven years ago with no complications. Patient admitted to have tiredness and dizziness for a few years but denied headache or visual symptoms. Pituitary hormone profile confirmed secondary hypothyroidism, secondary hypogonadism, low prolactin, low IGF-1 level but normal adrenal axi...

ea0073aep67 | Adrenal and Cardiovascular Endocrinology | ECE2021

Diagnosing Cushing’s syndrome due to Ectopic ACTH secretion warrants high Index of Suspicion- phenotypical features may not always present

Siddique Rana , Brahma Anupam

Patients with Cushing’s syndrome usually have characteristic phenotypical features but this is not always true in case of Ectopic ACTH secretion. This is mainly because this develops more acutely and underlying malignancy can cause significant weight loss. We report a 71 years old male with background of Prostatic malignancy who was found to have new profound hypokalaemia which was resistant to treatment. There were no signs of Cushing’s syndrome but index of suspici...

ea0065p240 | Metabolism and Obesity | SFEBES2019

Safe use of variable rate intravenous insulin infusion: a trust wide audit

Siddique Rana , Tauni Rahat Ali

Aims and objectives: Variable rate insulin infusion (VRII) is commonly used to achieve normoglycaemia in hospitalised patients. Joint British Diabetes Society (JBDS) produced guidelines on VRIII in 2014 to minimise complications related to inpatient VRII use. Local guidance along with a new VRII chart was introduced in 2017 at the West Suffolk NHS Foundation Trust and staff training provided. We performed an audit to review compliance to national and local VRII guidance.<p...

ea0065p435 | Thyroid | SFEBES2019

Early diagnosis and prompt treatment of severe thyrotoxicosis in patients with congestive cardiac failure is critical: lessons from a case of type 1 amiodarone induced severe thyrotoxicosis

Siddique Rana , Ai Tauni Rahat

Cardiac failure is a rare manifestation of thyrotoxicosis in patients without heart disease. However, patients with prior cardiac failure are at high risk of decompensation with thyrotoxicosis. Amiodarone is a widely used antiarrhythmic agent and amiodarone induced thyrotoxicosis (AIT) is not an uncommon complication. We present a case. A 48-year old male with intermittent atrial flutter, dilated cardiomyopathy, myocardial infarction and stroke was referred for severe thyrotox...

ea0070aep523 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Diabetic muscle infarction: A life changing diagnosis with poor long term prognosis

Manjunath Pramod , Siddique Rana , Rajagopal Vivek , Tauni Rahat

A 64 year old Caucasian man with long standing type 1 diabetes and complications of retinopathy, neuropathy and nephropathy was referred with suspected deep venous thrombosis (DVT) in the left lower limb. He had a week’s history of worsening pain and swelling in the medial left thigh and struggled to weight bear on that leg. He felt unwell a day before admission and was found to have hyperosmolar hyperglycaemic state with ketosis on admission. Ultrasound Doppler was nega...